Synthesis, characterization and antibacterial evaluation of new pyridyl-thiazole hybrids of sulfonamides


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Sahin Z., Biltekin S. N., YURTTAŞ L., DEMİRAYAK Ş.

ISTANBUL JOURNAL OF PHARMACY, cilt.51, sa.1, ss.67-72, 2021 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 51 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.26650/istanbuljpharm.2020.0083
  • Dergi Adı: ISTANBUL JOURNAL OF PHARMACY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.67-72
  • Anahtar Kelimeler: Sulfonamide, thiazole, antibacterial, PATHOGENESIS
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background and Aims: Sulfonamide drugs are a very old and noted group of small molecules, and are still one of the most important antimicrobial compounds. In this study, starting from sulfonamide drugs, new original compounds containing frequent and functional rings such as thiazole and pyridine were synthesized and their antimicrobial effects were evaluated.