Extended Release PLGA Nanoparticles for Chronic Pain

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Öztürk A. A., Martin Banderas L., Cayero Otero M. D., Yenilmez E., Yazan E. Y.

12. İnternation Symposium on Pharmaceutical Sciences (ISOPS 12), Ankara, Turkey, 26 - 29 June 2018, pp.281

  • Publication Type: Conference Paper / Full Text
  • City: Ankara
  • Country: Turkey
  • Page Numbers: pp.281
  • Anadolu University Affiliated: Yes


The pain situation has a very important effect on the biological, psychological, sociological and economic situation of the patient (1). Dexketoprofen trometamol (DT) has been developed as a water-soluble trometamine salt. DT is a rapidly acting analgesic agent in the treatment of painful musculoskeletal disorders such as back pain and osteoarthritis (2). In this study; DT loaded PLGA Nanoparticles (NPs) formulated with Double emulsions Solvent evaporation method which is the most suitable method for preparing PLGA NPs for hydrophilic drugs.