Synthesis and Anticandidal Activities of Some Aryl (5-Chloro-Benzofuran-2-yl) Ketoximes

KARABURUN A. Ç.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.16, sa.4, ss.427-436, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.2174/1570180816666181207155701
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.427-436
  • Anahtar Kelimeler: Aryl (5-chloro-benzofuran-2-yl) ketoximes, Anticandidal activity, Ergosterol inhibition, 14-alpha demethylase, docking study, antifungal activity, INVASIVE FUNGAL-INFECTIONS, MOLECULAR-BASIS, BENZOFURAN, ANTIFUNGAL, DISCOVERY, DESIGN, DERIVATIVES, RESISTANCE, EPIDEMIOLOGY, OPTIMIZATION
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: In this study, some aryl (5-chloro-benzofuran-2-yl) ketoximes and their ethers were synthesised to evaluate their antifungal activity against C. albicans, C. glabrata, C. krusei, and C. parapsilosis.