Microbial transformation of (-)-carvone

DEMİRCİ F., Noma Y., Kirimer N., Baser K.

ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES, vol.59, no.5-6, pp.389-392, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 5-6
  • Publication Date: 2004
  • Doi Number: 10.1515/znc-2004-5-618
  • Journal Name: ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.389-392
  • Keywords: (-)-carvone, microbial transformation, antimicrobial activity, ESSENTIAL OILS, BIOTRANSFORMATION, CONSTITUENTS, MONOTERPENES, PRODUCTS
  • Anadolu University Affiliated: Yes

Abstract

The cyclic monoterpene ketone (-)-carvone was metabolized by the plant pathogenic fungus Absidia glauca. After 4 days of incubation, the diol 10-hydroxy-(+)-neodihydrocarveol was formed. The absolute configuration and structure of the crystalline substance was identified by means of X-ray diffraction and by spectroscopic techniques (MS, IR and NMR). The antimicrobial activity of the substrate and metabolite was assayed with human pathogenic microorganisms.