Synthesis and Evaluation of Heterocycles Based Chalcone Derivatives as Anti-proliferative Agents

KAYA ÇAVUŞOĞLU B., ATLI EKLİOĞLU Ö., Gormus G., ÖZKAY Y., KAPLANCIKLI Z. A.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.18, sa.7, ss.1044-1053, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18 Sayı: 7
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1871520618666180105163657
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1044-1053
  • Anahtar Kelimeler: Chalcone, antiproliferative activity, cytotoxicity, apoptotic pathway, derivatives, heterocycles, VITRO ANTITUMOR-ACTIVITY, ANTICANCER ACTIVITIES, APOPTOSIS, CYTOTOXICITY, REACTIVITY, PARADIGM, ANALOGS, DESIGN
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: The lack of selectivity and development of drug-resistance encourage researchers to search for novel, more efficient and multi-targeted agents with less toxicity.