The aim of this study was the compare the properties of hydroxyapatite as a function of two different methods (chemical and biomimetic precipitation). Powder products were called as chemical hydroxyapatite for chemical method and biomimetic hydroxyapatite for biomimetic method. Precipitated powders with both methods were characterized by Fourier transform infrared, X-ray diffraction, X-ray fluorescence and measurements of hardness and density. Chemical analysis results showed that dried-biomimetic hydroxyapatite sample consists of hydroxyapatite [Ca10PO4)6(OH)2] as main phase and beta-tricalcium phosphate (fi-TCP) as secondary phase and dried-chemical hydroxyapatite sample also includes pure hydroxyapatite phase. Chemical hydroxyapatite and biomimetic hydroxyapatite powders were sintered using by spark plasma sintering method. Vickers hardness values of sintered disk samples were measured. Furthermore chemical structure of the final products was analyzed. Also density values of chemical hydroxyapatite and biomimetic hydroxyapatite disks were measured. Finally it is concluded that different precipitation methods affect hydroxyapatite properties and this can be an advantage for biomedical applications.