Copy For Citation
YURTTAŞ L., KAPLANCIKLI Z. A., TEMEL H. E., AKALIN ÇİFTÇİ G.
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.42, no.2, pp.169-180, 2017 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
42
Issue:
2
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Publication Date:
2017
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Doi Number:
10.1515/tjb-2016-0207
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Journal Name:
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
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Page Numbers:
pp.169-180
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Keywords:
Tetrazole, Hydrazone, Anticholinesterase, AChE, BuChE, Cytotoxicity, ACETYLCHOLINESTERASE INHIBITORS, CHOLINESTERASE-INHIBITORS, BIOLOGICAL-ACTIVITIES, ALZHEIMERS-DISEASE, DESIGN, CHEMISTRY, SUGARS, MOIETY
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Anadolu University Affiliated:
Yes
Abstract
Objective(s): The synthesis of new N'-arylidene-4-[(1phenyl- 1H-tetrazole-5-yl) thio] butanoylhydrazide derivatives (1-26) and investigation of their potential anticholinesterase (AChE), butyrylcholinesterase (BuChE) enzyme inhibition activities and also cytotoxic properties on mouse embryonic fibroblast cells (NIH/3T3) were aimed in this work.