Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line, A549

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Koparal A. T., Zeytinoglu M.

15th Annual Meeting of the Japanese-Association-for-Animal-Cell-Technology, Fuchu, Japan, 11 - 15 November 2002, pp.207-211 identifier identifier

  • Publication Type: Conference Paper / Full Text
  • Doi Number: 10.1023/b:cyto.0000039917.60348.45
  • City: Fuchu
  • Country: Japan
  • Page Numbers: pp.207-211
  • Anadolu University Affiliated: Yes


Carvacrol, the predominant monoterpene in many essential oils of Labitae including Origanum, Satureja, Thymbra, Thymus, and Corydothymus has substantial antibacterial, anti fungal, antihelmintic, insecticial, analgesic and antioxidant activities. In this study a human non-small cell lung cancer (NSCLC) cell line, A549 was used. Approximately 75% of lung cancer is non-small cell carcinoma (NSCLC) which comprises several histologic types: squamous cell, adenocarcinoma and large cell carcinoma. It was reported that the proportion of lung tumors diagnosed as adenocarcinoma has increased. For this reason A549 cell line was chosen for this study.