A preliminary investigation of anticancer activity of novel benzothiazole derivatives against A549 lung carcinoma cell line
TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.42, no.5, pp.535-544, 2017 (SCI-Expanded, Scopus, TRDizin)
- Publication Type: Article / Article
- Volume: 42 Issue: 5
- Publication Date: 2017
- Doi Number: 10.1515/tjb-2017-0015
- Journal Name: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Page Numbers: pp.535-544
- Keywords: Benzothiazole, Synthesis, Lung cancer, Cytotoxicity, Apoptosis, ANTITUMOR BENZOTHIAZOLES, IN-VITRO, BIOLOGICAL-PROPERTIES, CANCER, SURVIVAL, 2-(4-AMINOPHENYL)BENZOTHIAZOLES, CYTOTOXICITY, POTENT, AGENTS, VIVO
- Anadolu University Affiliated: Yes
Abstract
Objective(s): In this study, it was aimed to synthesize new chemotherapeutic agents based on known antiproliferative properties of benzothiazol-2-amine moiety. The antitumor activity of the newly synthesized compounds was determined against A549 lung cancer cell lines.