LETTERS IN DRUG DESIGN & DISCOVERY, vol.18, no.4, pp.372-386, 2021 (SCI-Expanded)
Article / Article
LETTERS IN DRUG DESIGN & DISCOVERY
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE
Thiazole, hydrazone, A549, C6, apoptosis, anticancer activity, BIOLOGICAL EVALUATION, THIAZOLE DERIVATIVES, LUNG-CANCER, PYRIDINE-DERIVATIVES, DRUG-RESISTANCE, IN-SILICO, CYTOTOXICITY, DASATINIB, ANALOGS, GLIOMA
Anadolu University Affiliated:
Background: Recently, researchers have been warning about the increased mortality of the various cancer types. Also, the lung adenocarcinoma and the glioma types are burning issues for world's health due to late or wrong diagnosis and/or insufficient treatment methods. For this purpose, our research group designed and synthesized novel 4,5-dimethyl thiazole-hydrazone derivatives which were tested against cancer and normal cell lines to understand the structure-activity relationship (SAR).