Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives

Karaburun A. Ç., Gündoğdu-Karaburun N., Yurttaş L., Kayağil İ., Demirayak Ş.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.16, no.2, pp.111-118, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.2174/1570180815666180606081042
  • Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.111-118
  • Keywords: Anticancer activity, aurone analogue, benzothiazoleacetamide, 2,3-dihydro-1H-inden-1-one, thiazoleacetamide, leukaemia, BIOLOGICAL EVALUATION, DRUG DISCOVERY, POTENT, INHIBITORS, CHROMAN-4-ONE, FLAVONES, CHROMONE, DESIGN
  • Anadolu University Affiliated: Yes

Abstract

Background: The synthesis of 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2ylidene) methyl)phenoxy]-N-(heteroaryl)acetamide derivatives and the investigation of their anticancer activity were studied.