Oxidation of Thymol and Carvacrol to Thymoquinone with KHSO5 Catalyzed by Iron Phthalocyanine Tetrasulfonate in a Methanol-Water Mixture

Gunay T., ÇİMEN Y., Karabacak R. B., TÜRK H.

CATALYSIS LETTERS, vol.146, no.11, pp.2306-2312, 2016 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 146 Issue: 11
  • Publication Date: 2016
  • Doi Number: 10.1007/s10562-016-1850-2
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.2306-2312
  • Keywords: Phthalocyanine tetrasulfonate, Peroxymonosulfate, Thymol, Carvacrol, Oxidation < Processes and reactions, NIGELLA-SATIVA, HYDROGEN-PEROXIDE, METAL-COMPLEXES, MONOTERPENES, PHENOLS, OIL, 2,3,6-TRIMETHYLPHENOL, DEGRADATION, DERIVATIVES, GENERATION
  • Anadolu University Affiliated: Yes


The oxidation of thymol and carvacrol to thymoquinone with potassium peroxymonosulfate (KHSO5) catalyzed by iron phthalocyanine tetrasulfonate (FePcTS) in a methanol (4.0 mL)-water (0.5 mL) mixture has been carried out. In a typical reaction, the amounts of the substrate, oxidant, and catalyst were 0.300, 0.600, and 1 x 10(-3) millimoles, respectively. Ninety-nine percent conversions of thymol in 1 h and of carvacrol in 30 min were achieved at ambient temperature. The major product of both oxidation reactions was thymoquinone (2-isopropyl-5-methylbenzoquinone, TQ) and the reactions also yielded polymeric products poly(2-isopropyl-5-methyl-1,4-phenylene oxide) and poly(5-isopropyl-2-methyl-1,3-phenylene oxide). These polymers are novel and not reported before. When H2O2 or Bu (t) OOH was used as the oxidant, the yield of TQ was < 1 %.