Synthesis of 4-hydroxyquinoline-2,3-dicarboxylates using N-(2-aminobenzoyl)benzotriazoles

ÇELİK İ., Yildiz F.

TETRAHEDRON, vol.73, no.27-28, pp.3878-3882, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 27-28
  • Publication Date: 2017
  • Doi Number: 10.1016/j.tet.2017.05.058
  • Journal Name: TETRAHEDRON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC), Current Chemical Reactions (CCR)
  • Page Numbers: pp.3878-3882
  • Keywords: Benzotriazole, 4-Hydroxyquinoline-2,3-dicarboxylate, N-(2-aminobenzoyl)benzotriazole, Annulation, Aza-Michael addition, INHIBITORS, MODEL
  • Anadolu University Affiliated: Yes


A method for the preparation of 4-hydroxyquinoline-2,3-dicarboxylates has been developed by aza-Michael addition reaction of N-(2-aminobenzoyl)benzotriazoles with dimethyl acetylenedicarboxylate. 4-Hydroxyquinoline-2,3-dicarboxylates were obtained in moderate to good yields (53-87%). (C) 2017 Elsevier Ltd. All rights reserved.