Antifungal effects of some oxadiazole derivatives on pathogenic molds Bazı oksadiazol türevlerinin patojenik küfler üzerindeki antifungal etkileri

KAPLANCIKLI Z. A., ALTINTOP M. D., DEMİREL R.

Turkish Journal of Pharmaceutical Sciences, cilt.10, sa.1, ss.145-150, 2013 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 1
  • Basım Tarihi: 2013
  • Dergi Adı: Turkish Journal of Pharmaceutical Sciences
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.145-150
  • Anahtar Kelimeler: Antifungal activity, Aspergillus, Fusarium, Oxadiazole
  • Anadolu Üniversitesi Adresli: Evet

Özet

Some oxadiazole derivatives were tested in vitro against Aspergillus parasiticus, Aspergillus flavus, Aspergillus niger, Fusarium solani, Fusarium moniliforme and Stachybotrys chartarum. All compounds showed the highest antifungal activity against S. chartarum. Among these compounds (3a-j), compounds 3a, 3c, 3d, 3e, 3i, 3j exhibited the same level of antifungal activity against all tested mold species. Compounds 3a, 3c, 3d, 3e possess 4-methoxyphenoxymethyl moiety on oxadiazole ring, whereas compounds 3i and 3j carry 2-cyclohexylethyl moiety on oxadiazole ring.