Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line, A549

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Koparal A., Zeytinoglu M.

CYTOTECHNOLOGY, vol.43, no.1-3, pp.149-154, 2003 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 1-3
  • Publication Date: 2003
  • Doi Number: 10.1023/b:cyto.0000039917.60348.45
  • Journal Name: CYTOTECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.149-154
  • Keywords: A549 cells, apoptosis, carvacrol, cell morphology, lung cancer, APOPTOSIS
  • Anadolu University Affiliated: No

Abstract

Carvacrol, the predominant monoterpene in many essential oils of Labitae including Origanum, Satureja, Thymbra, Thymus, and Corydothymus has substantial antibacterial, antifungal, antihelmintic, insecticial, analgesic and antioxidant activities. Approximately 75% of lung cancer is non-small cell carcinoma (NSCLC) which comprises several histologic types squamous cell, adenocarcinoma and large cell carcinoma. It was reported that the portion of lung tumors diagnosed as denocarcinoma has increased. Thus a human non-small cell lung cancer (NSCLC) cell line, A549 was chosen for this study.