Effects of carvacrol on a human non-small cell lung cancer (NSCLC) cell line, A549

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Koparal A., Zeytinoglu M.

CYTOTECHNOLOGY, cilt.43, sa.1-3, ss.149-154, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 1-3
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1023/b:cyto.0000039917.60348.45
  • Dergi Adı: CYTOTECHNOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.149-154
  • Anahtar Kelimeler: A549 cells, apoptosis, carvacrol, cell morphology, lung cancer, APOPTOSIS
  • Anadolu Üniversitesi Adresli: Hayır

Özet

Carvacrol, the predominant monoterpene in many essential oils of Labitae including Origanum, Satureja, Thymbra, Thymus, and Corydothymus has substantial antibacterial, antifungal, antihelmintic, insecticial, analgesic and antioxidant activities. Approximately 75% of lung cancer is non-small cell carcinoma (NSCLC) which comprises several histologic types squamous cell, adenocarcinoma and large cell carcinoma. It was reported that the portion of lung tumors diagnosed as denocarcinoma has increased. Thus a human non-small cell lung cancer (NSCLC) cell line, A549 was chosen for this study.