In vitro antimicrobial evaulation of Ferulago Sandrasica Peșmen & Quézel Herba and root essential oil

Sucu M., Kırcı D., DEMİRCİ B., DUMAN H., KILIÇ C. S., GÜRBÜZ İ.

Natural Volatiles and Essential Oils, vol.6, no.4, pp.13-20, 2019 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 4
  • Publication Date: 2019
  • Journal Name: Natural Volatiles and Essential Oils
  • Journal Indexes: Scopus
  • Page Numbers: pp.13-20
  • Keywords: Antimicrobial activity, Apiaceae, Ferulago sandrasica, Herba, Root
  • Anadolu University Affiliated: Yes

Abstract

© 2019, Badebio Biotechnololgy Ltd. All rights reserved.Ferulago sandrasica Peșmen & Quézel was initially collected from Köyceğiz, which is endemic species for Turkey. The air dried herbal parts and roots were evaluated for their volatile compositions and antimicrobial activity. The essential oils were obtained by hydrodistillation, which were subsequently analyzed by GC-FID and GC-MS, respectively. The main components of the herb essential oil were identified as α-pinene (26.4%), caryophyllene oxide (6.1%), camphene (5.1%), trans-verbenol (5%); whereas the root essential oil compounds were α-pinene (27.9%), limonene (26.1%), δ-3-carene (14.2%), myrcene (7.6%), terpinolene (11%), respectively. In addition, the essential oils were evaluated for their in vitro antimicrobial activity using a broth microdilution method against the human pathogens Escherichia coli, Staphylococcus aureus, Salmonella typhimurium, Bacillus subtilis, and the yeasts Candida tropicalis, C. parapsilosis. The activity results showed that F. sandrasica was effective against the tested pathogens with the minimum inhibition concentrations (MIC) of 2.5-10 mg/mL.