Larvicidal activity of some secondary lichen metabolites against the mosquito Culiseta longiareolata Macquart (Diptera: Culicidae)

ÇETİN H., TUFAN ÇETİN Ö., Turk A. O., Tay T., Candan M., Yanikoglu A., ...More

NATURAL PRODUCT RESEARCH, vol.26, no.4, pp.350-355, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.1080/14786411003774296
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.350-355
  • Keywords: Culiseta, larvicide, lethal activity, lichen, mosquito, ANTIMICROBIAL ACTIVITY, ACID CONSTITUENTS, CULEX-PIPIENS, EXTRACTS, VECTOR
  • Anadolu University Affiliated: Yes


The larvicidal activity of some lichen metabolites, (+)-usnic acid, atranorin, 3-hydroxyphysodic acid and gyrophoric acid, against the second and third instar larvae of the mosquito Culiseta longiareolata were studied. All metabolites caused high larvicidal activities. When metabolites were compared on the basis of their LC50 values, the order of increasing toxicity was as follows: gyrophoric acid (0.41 ppm) > (+)-usnic acid (0.48 ppm) > atranorin (0.52 ppm) > 3-hydroxyphysodic acid (0.97 ppm). However, when LC90 values were compared, the order of toxicity was (+)-usnic acid (1.54 ppm) > gyrophoric acid (1.93 ppm) > 3-hydroxyphysodic acid (4.33 ppm) > atranorin (5.63 ppm). In conclusion, our results found that lichen secondary metabolites may have a promising role as potential larvicides.