Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles

ÇELİK İ., Abdel-Fattah A. A. A.

TETRAHEDRON, cilt.65, sa.25, ss.4923-4929, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 65 Sayı: 25
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1016/j.tet.2009.02.070
  • Dergi Adı: TETRAHEDRON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
  • Sayfa Sayıları: ss.4923-4929
  • Anadolu Üniversitesi Adresli: Evet

Özet

N-Protected dipeptidoylbeiizotriazoles react with aqueous ammonia to give dipeptide primary amides (77-98%) and with N-unprotected alpha-amino amides to afford tripeptide primary amides (82-86%). (C) 2009 Published by Elsevier Ltd.