Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles

ÇELİK, İLHAMİ; Abdel-Fattah, Ashraf

doi:10.1016/j.tet.2009.02.070

Convenient synthesis of C-terminal di- and tri-peptide amides from N-protected dipeptidoylbenzotriazoles

ÇELİK İ., Abdel-Fattah A. A. A.

TETRAHEDRON, cilt.65, sa.25, ss.4923-4929, 2009 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 65 Sayı: 25
Basım Tarihi: 2009
Doi Numarası: 10.1016/j.tet.2009.02.070
Dergi Adı: TETRAHEDRON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
Sayfa Sayıları: ss.4923-4929
Anadolu Üniversitesi Adresli: Evet

Özet

N-Protected dipeptidoylbeiizotriazoles react with aqueous ammonia to give dipeptide primary amides (77-98%) and with N-unprotected alpha-amino amides to afford tripeptide primary amides (82-86%). (C) 2009 Published by Elsevier Ltd.