Synthesis, characterization and antibacterial evaluation of new pyridyl-thiazole hybrids of sulfonamides

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Sahin Z., Biltekin S. N., YURTTAŞ L., DEMİRAYAK Ş.

ISTANBUL JOURNAL OF PHARMACY, vol.51, no.1, pp.67-72, 2021 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 51 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.26650/istanbuljpharm.2020.0083
  • Journal Name: ISTANBUL JOURNAL OF PHARMACY
  • Journal Indexes: Emerging Sources Citation Index (ESCI)
  • Page Numbers: pp.67-72
  • Keywords: Sulfonamide, thiazole, antibacterial, PATHOGENESIS
  • Anadolu University Affiliated: Yes

Abstract

Background and Aims: Sulfonamide drugs are a very old and noted group of small molecules, and are still one of the most important antimicrobial compounds. In this study, starting from sulfonamide drugs, new original compounds containing frequent and functional rings such as thiazole and pyridine were synthesized and their antimicrobial effects were evaluated.