Rhanterium epapposum Oliv. essential oil: Chemical composition and antimicrobial, insect-repellent and anticholinesterase activities

DEMİRCİ B., Yusufoglu H. S., Tabanca N., TEMEL H. E., Bernier U. R., Agramonte N. M., ...Daha Fazla

SAUDI PHARMACEUTICAL JOURNAL, cilt.25, sa.5, ss.703-708, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.jsps.2016.10.009
  • Dergi Adı: SAUDI PHARMACEUTICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.703-708
  • Anahtar Kelimeler: Rhanterium epapposum, Essential oil, Botanical repellents, Antimicrobial activity, AChE and BuChE inhibition, YELLOW-FEVER MOSQUITO, BIOASSAY
  • Anadolu Üniversitesi Adresli: Evet

Özet

The essential oil (EO) of the aerial parts of Rhanterium epapposum Oliv. (Asteraceae), was obtained by hydrodistillation. The oil was subsequently analyzed by both GC-FID and GC-MS, simultaneously. Forty-five components representing 99.2% of the oil composition were identified. The most abundant compounds were camphene (38.5%), myrcene (17.5%), limonene (10.1%) and alpha-pinene (8.7%). Referring to the ethnobotanical utilization, an insecticidal assay was performed, where the oil repelled the yellow fever mosquito Aedes aegypti L. at a minimum effective dose (MED of 0.035 +/- 0.010 mg/cm(2)) compared to the positive control DEET (MED of 0.015 +/- 0.004 mg/cm(2)). Additionally, the in vitro antimicrobial activity against a panel of pathogens was determined using a microdilution method. The acetyl- and butyrylcholine esterase inhibitory activities were measured using the colorimetric Ellman method. The bioassay results showed that the oil was rather moderate in antimicrobial and cholinesterase inhibitions when compared to the standard compounds. (C) 2016 The Authors. Production and hosting by Elsevier B.V. on behalf of King Saud University.