Antinociceptive, antiinflammatory, and antioxidant activities of the ethanol extract of Crataegus orientalis leaves

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Bor Z., ARSLAN R., BEKTAŞ TÜRKMEN N., Pirildar S., DÖNMEZ A. A.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.42, no.2, pp.315-324, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 42 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.3906/sag-1011-1304
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.315-324
  • Keywords: Crataegus orientalis, hawthorn, antinociception, antiinflammation, antioxidant, METHANOLIC EXTRACT, STEM BARK, IN-VITRO, CONSTITUENTS, CARRAGEENAN, RECEPTOR, DRUGS, MICE
  • Anadolu University Affiliated: Yes

Abstract

Aim: To determine the in vitro antioxidant activity and to investigate the possible antinociceptive and antiinflammatory effects of the ethanol extract of Crataegus orientalis leaves. The medicinal use of extracts prepared from the leaves, flowers, and fruits of Crataegus (hawthorn) dates back to ancient times. It has been proposed that its antioxidant constituents account for these beneficial therapeutic effects.