Antinociceptive, antiinflammatory, and antioxidant activities of the ethanol extract of Crataegus orientalis leaves

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Bor Z., ARSLAN R., BEKTAŞ TÜRKMEN N., Pirildar S., DÖNMEZ A. A.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.42, sa.2, ss.315-324, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 42 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3906/sag-1011-1304
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.315-324
  • Anahtar Kelimeler: Crataegus orientalis, hawthorn, antinociception, antiinflammation, antioxidant, METHANOLIC EXTRACT, STEM BARK, IN-VITRO, CONSTITUENTS, CARRAGEENAN, RECEPTOR, DRUGS, MICE
  • Anadolu Üniversitesi Adresli: Evet

Özet

Aim: To determine the in vitro antioxidant activity and to investigate the possible antinociceptive and antiinflammatory effects of the ethanol extract of Crataegus orientalis leaves. The medicinal use of extracts prepared from the leaves, flowers, and fruits of Crataegus (hawthorn) dates back to ancient times. It has been proposed that its antioxidant constituents account for these beneficial therapeutic effects.