Antibacterial, anticandidal and antioxidant properties of Tanacetum argenteum (Lam.) Willd. subsp flabellifolium (Boiss. & Heldr.) grierson

KÖSE Y. B., İŞCAN G., GÖGER F., DEMİRCİ B., Elmaci C.

PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, cilt.30, sa.6, ss.2047-2052, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 6
  • Basım Tarihi: 2017
  • Dergi Adı: PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2047-2052
  • Anahtar Kelimeler: Tanacetum argenteum subsp flabellifolium, essential oil, methanol extract, antimicrobial, antioxidant, GC-FID, GC/MS, LC-MS/MS, ESSENTIAL OILS, ENANTIOMERIC DISTRIBUTION, SCHULTZ BIP., LC-MSN, L., PRODUCTS, EXTRACT, TURKEY
  • Anadolu Üniversitesi Adresli: Evet

Özet

In the present study hydrodistilled essential oil and total methanol extracts of Tanacetum argenteum subsp. flabellifolium have been evaluated for their antimicrobial and antioxidant effects. The chemical composition of the oil and the crude extract were determined by GC/FID, GC/MS and LC/DAD/ESI-MS systems respectively. beta-thujone (47.1%), a-pinene (19.1%) and a-thujone (10.5%) were the main compounds of the essential oil while the 5-O-caffeoylquinic acid, 1,5-O-dicaffeoylquinic acid, 4,5-O-dicaffeoylquinic acid were identified as flavonoid content of the crude extract. The oil and the methanol extract were demonstrated moderate antimicrobial effects (MIC range; 0,062-2,0 mg/mL) against 21 different pathogenic micro organism. Total phenolic content was determined as 63 mg GAE in g extract and the DPPH radical scavenging effect was determined as 0.16 mg/mL (IC50) and TEAC was determined as 0.21mMol.