Antibacterial activities of the methanol extracts, fractions and compounds from Harungana madagascariensis Lam. ex Poir. (Hypericaceae)

Tankeo S. B., Damen F., Sandjo L. P., ÇELİK İ., Tane P., Kuete V.

JOURNAL OF ETHNOPHARMACOLOGY, cilt.190, ss.100-105, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 190
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.jep.2016.06.005
  • Dergi Adı: JOURNAL OF ETHNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.100-105
  • Anahtar Kelimeler: Antibacterial, Ferruginin A, Kaempferol-3-O-beta-D-glucopyranoside, Madagascin, Crude extract, Multi-drug resistance, CAMEROONIAN MEDICINAL-PLANTS, ANTIMICROBIAL ACTIVITY, STEM BARK, BACTERIA, MORACEAE, CONSTITUENTS, PRODUCTS
  • Anadolu Üniversitesi Adresli: Evet

Özet

Ethnopharmacological relevance: Harungana madagascariensis Lam. ex Poir. (Hypericaceae) is used in folk medicine to treat a variety of human ailments, mainly antibacterial, antifungal, antiviral and viral infections. In the present study, the methanol extract from the leaves (HML) and bark (HMB) of this plant as well as fractions (HMBa-c), sub-fractions (HMBal-5) and compounds isolated from HMBa and HMBb namely betulinic acid (1), madagascin (2), ferruginin A (3) and Kaempferol-3-O-beta-D-glucopyranoside (4) were tested for their antimicrobial activities against a panel of 28 g-negative bacteria including multi drug resistant (MDR) phenotypes.