Synthesis characterization and biological activity of mixed ligand silver(I) complex of 2-benzimidazolylurea and triphenylphosphine

POYRAZ M., Berber H., Banti C. N., Kourkoumelis N., Manos M. J., Hadjikakou S. K.

POLYHEDRON, vol.128, pp.95-103, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 128
  • Publication Date: 2017
  • Doi Number: 10.1016/j.poly.2017.03.011
  • Journal Name: POLYHEDRON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.95-103
  • Keywords: Biological inorganic chemistry, Silver(I) metallo-drugs, Urea derivative, Cells screening, Crystal structure, BREAST-CANCER CELLS, STRUCTURAL-CHARACTERIZATION, CRYSTAL-STRUCTURES, SALICYLIC-ACID, LINOLEIC-ACID, SOLID-STATE, ORGANOTIN(IV), GOLD(I), BIOSYNTHESIS, LIPOXYGENASE
  • Anadolu University Affiliated: Yes


The treatment with triphenylphosphine (TPP) in DMF solution of the white precipitation derived from the reaction of silver(I) nitrate with 2-benzimidazolylurea (BZIMU) results in the [Ag(TPP)(2)(BZIMU)NO3] (1) complex. The product was characterized by elemental analysis and spectroscopic techniques (FT-IR and H-1, C-13 NMR). Single crystal X-ray diffraction analysis of 1 have been carried out at 293 K. Mixed ligand complexes of silver(I) nitrate with urea derivatives and phosphines which exhibits significant biological effects are rare in the literature.