Antidepressant-like effect of gallic acid in mice: Dual involvement of serotonergic and catecholaminergic systems

CAN Ö. D., Turan N., DEMİR ÖZKAY Ü., ÖZTÜRK Y.

LIFE SCIENCES, vol.190, pp.110-117, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 190
  • Publication Date: 2017
  • Doi Number: 10.1016/j.lfs.2017.09.023
  • Journal Name: LIFE SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.110-117
  • Keywords: Gallic acid, Modified forced swimming test, Serotonergic system, Monoaminergic system, Tail suspension test, CHRONIC CEREBRAL HYPOPERFUSION, BRAIN TARGETED DELIVERY, TAIL SUSPENSION TEST, OXIDATIVE STRESS, BALB/C MICE, ANTIOXIDANT, CELL, INFLAMMATION, METABOLISM, PAROXETINE
  • Anadolu University Affiliated: Yes

Abstract

Aims: This study was planned to examine the antidepressant potency of gallic acid (30 and 60 mg/kg), a phenolic acid widely distributed in nature, together with its possible underlying monoaminergic mechanisms.