Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia

Dernek S., Ikizler M., Erkasap N., Ergun B., Koken T., Yilmaz K., ...Daha Fazla

SCANDINAVIAN CARDIOVASCULAR JOURNAL, cilt.38, sa.4, ss.245-254, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 4
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1080/14017430410035476
  • Dergi Adı: SCANDINAVIAN CARDIOVASCULAR JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.245-254
  • Anahtar Kelimeler: antioxidant, ischemia, pretreatment, reperfusion, resveratrol, RED WINE, VASORELAXING ACTIVITY, REPERFUSION INJURY, OXIDATIVE STRESS, FREE-RADICALS, CONSUMPTION, INHIBITION, QUERCETIN, MORTALITY, KINETICS
  • Anadolu Üniversitesi Adresli: Evet

Özet

Objective-The major objective of the present study is to evaluate the potential role of resveratrol (RVT), a natural antioxidant found in grapes and red wine, in protecting the myocardium from the deleterious effects of ischemia-reperfusion (I/R) injury using isolated rat hearts.