Cardioprotection with resveratrol pretreatment: improved beneficial effects over standard treatment in rat hearts after global ischemia
SCANDINAVIAN CARDIOVASCULAR JOURNAL, vol.38, no.4, pp.245-254, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 38 Issue: 4
- Publication Date: 2004
- Doi Number: 10.1080/14017430410035476
- Journal Name: SCANDINAVIAN CARDIOVASCULAR JOURNAL
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.245-254
- Keywords: antioxidant, ischemia, pretreatment, reperfusion, resveratrol, RED WINE, VASORELAXING ACTIVITY, REPERFUSION INJURY, OXIDATIVE STRESS, FREE-RADICALS, CONSUMPTION, INHIBITION, QUERCETIN, MORTALITY, KINETICS
- Anadolu University Affiliated: Yes
Abstract
Objective-The major objective of the present study is to evaluate the potential role of resveratrol (RVT), a natural antioxidant found in grapes and red wine, in protecting the myocardium from the deleterious effects of ischemia-reperfusion (I/R) injury using isolated rat hearts.