Antiproliferative effects of some N-benzylideneanilines

ÖZKAY Y., Incesu Z., IŞIKDAĞ İ., Yesilkaya M.

CELL BIOCHEMISTRY AND FUNCTION, sa.1, ss.102-106, 2008 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1002/cbf.1406
  • Dergi Adı: CELL BIOCHEMISTRY AND FUNCTION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.102-106
  • Anahtar Kelimeler: Schiff bases, N-benzylideneaniline, cytotoxic, proliferation, small lung (A549) and cervical (HeLa) cancer cell lines, SCHIFF-BASES, ANTICANCER, COMPLEXES, SPECTRA, NMR
  • Anadolu Üniversitesi Adresli: Evet

Özet

A series of Schiff bases including N-benzylideneaniline (NBA) nuclei were prepared. The chemical products obtained were characterized by mass spectometry (APCI), H-1 NMR, and IR spectroscopy in order to seek their cytotoxic and proliferation effects on human small lung (A549) and cervical (HeLa) cancer cell lines with biochemical assays. All of the synthesized compounds showed antiproliferative effects to different extents. Copyright (C) 2007 John Wiley & Sons, Ltd.