Antibacterial Activity and the Variation of Tanacetum parthenium (L.) Schultz Bip. Essential Oils from Turkey

Creative Commons License

Polatoglu K., DEMİRCİ F., Demirci B., GÖREN N., BAŞER K. H. C.

JOURNAL OF OLEO SCIENCE, vol.59, no.4, pp.177-184, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.5650/jos.59.177
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.177-184
  • Keywords: Tanacetum parthenium, Asteraceae, essential oils, chemotypes, camphor, trans-chrysanthenyl acetate, camphene, DPPH radical scavenging, antibacterial activity, Vibrio fischeri toxicity, FEVERFEW, ASTERACEAE
  • Anadolu University Affiliated: Yes


Water-distilled essential oils from herbal parts of Tanacetum parthenium from two different localities in Turkey were analyzed by GC and GC/MS. The essential oil of T. parthenium collected from Davutpasa-Istanbul location were characterized with camphor 49%, trans-chrysanthenyl acetate 22.1% and camphene 9.4%. Second plant sample is collected from the remote east end of the country Savsat-Ardahan location. The essential oil from this location was characterized with camphor 60.8% and camphene 6.8%. Unlike the former this sample contains trans-chrysanthenyl acetate in trace amount and cis- chrysanthenyl acetate in very small amount (0.6%) which is not present in the first sample. Antibacterial activity of the oils were evaluated for five Gram (+) and five Gram (-) bacteria by using a broth microdilution assay. The highest activity was observed on Bacillus subtilis, Staphylococcus aureus and methicillin-resistant S.aureus however when compared with positive control oils showed higher MIC values. The oil of Istanbul-sample showed highest activity on B. subtilis (125 mu g/mL) and methicillin-resistant S. aureus (125 mu g/mL) which is two fold concentration when compared with the positive control chloramphenicol (62.5 mu g/mL). The oil of Ardahan sample showed the highest activity on S.aureus (125 mu g/mL) which is likewise two fold concentration of the positive control chloramphenicol (62.5 mu g/mL). DPPH scavenging activity was 59.3% of the oil from Davutpasa at 15 mg/mL, concentration. When compared to positive control alpha-tocopherol (94.6%) Savsat oil (28.2%) showed low and Davutpasa oil showed medium DPPH scavenging activity. All of the oils showed toxicity to Vibrio fischeri in the TLC-bioluminescence assay.