Cannabinoid system involves in the analgesic effect of protocatechuic acid

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Dikmen D. Y., Okcay Y., ARSLAN R., BEKTAŞ TÜRKMEN N.

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES, vol.27, no.2, pp.605-612, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.1007/s40199-019-00288-x
  • Journal Name: DARU-JOURNAL OF PHARMACEUTICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.605-612
  • Keywords: Protocatechuic acid, Pain, CB1 receptor, CB2 receptor, Cannabinoid system, ANIMAL-MODELS, ENDOCANNABINOID SYSTEM, INFLAMMATORY PAIN, RECEPTOR, ANTINOCICEPTION, AGONIST, MECHANISMS, NOCICEPTION, ACTIVATION, NEURONS
  • Anadolu University Affiliated: Yes

Abstract

Background Protocatechuic acid is an antioxidant which is shown to have analgesic activity in limited studies. However, the mechanisms of action remain unclear.