The effects of atorvastatin on antioxidant/antiinflammatory properties of HDLs in hypercholesterolemics

AKALIN ÇİFTÇİ G., Ertorun I., AKALIN A., ALATAŞ İ. Ö., MUSMUL A.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, sa.2, ss.345-351, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 45 Sayı: 2
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1311-91
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.345-351
  • Anahtar Kelimeler: Antioxidant/antiinflammatory high-density lipoprotein, atorvastatin, hypercholesterolemia, oxidative stress, ASYMMETRIC DIMETHYLARGININE, REDUCTASE INHIBITORS, OXIDATIVE STRESS, APOLIPOPROTEIN-B, SERUM, PARAOXONASE-1, LIPOPROTEIN(A), CHOLESTEROL, EXPRESSION, THERAPY
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background/aim: Hypercholesterolemia is characterized by changes in lipid profile, nitric oxide pathway, and oxidative stress markers, but functions of high-density lipoprotein (HDL) were not well established in hypercholesterolemic subjects treated with atorvastatin. In this study, we aimed to evaluate effects of atorvastatin treatment on functionality of HDL, oxidative stress, and endothelial functions in hypercholesterolemic subjects.