Opioid system mediated anti-nociceptive effect of agomelatine in mice

Kasap M., CAN Ö. D.

LIFE SCIENCES, cilt.163, ss.55-63, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 163
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.lfs.2016.08.031
  • Dergi Adı: LIFE SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.55-63
  • Anahtar Kelimeler: Agomelatine, Opioid receptor, Hot-plate test, Tail-clip test, Acetic acid-induced writhing test, DOUBLE-BLIND, ANTIDEPRESSANT EFFICACY, ANALGESIC ACTION, POOLED ANALYSIS, MELATONIN, RECEPTOR, MT2, HYPERALGESIA, INVOLVEMENT, NOCICEPTION
  • Anadolu Üniversitesi Adresli: Evet

Özet

Aims: This study was planned to examine the antinociceptive efficacy of agomelatine against acute mechanical, thermal, and chemical nociceptive stimuli, as well as to determine the opioid receptor subtypes mediating these effects.