HPLC profiling and quantification of active principles in leaves of Hedera helix L.

Demirci B., Goppel M., DEMİRCİ F., Franz G.

Pharmazie, vol.59, no.10, pp.770-774, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 59 Issue: 10
  • Publication Date: 2004
  • Journal Name: Pharmazie
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.770-774
  • Anadolu University Affiliated: Yes


Ivy (Hedera helix L., Araliaceae), is an evergreen medicinal and ornamental plant. Depending on leaf polymorphism different shaped ivy leaves were extracted and subsequently analyzed by reversed-phase high performance liquid chromatography (RP-HPLC). Quantitative determination of its most prominent saponins hederacoside C (1) and α-hederin (2) from different ivy leaf extracts were detected, validated and optimized for quick profiling. The linearity of response, repeatability and reproducibility of the applied RP-HPLC method are reported.