Stereoselective and regioselective synthesis of N-substituted methyl 2-((azolyl)methyl)-3-arylacrylates from Baylis-Hillman acetates
TURKISH JOURNAL OF CHEMISTRY, cilt.41, sa.3, ss.323-334, 2017 (SCI-Expanded, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 3
- Basım Tarihi: 2017
- Doi Numarası: 10.3906/kim-1607-35
- Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.323-334
- Anahtar Kelimeler: Imidazole, benzimidazole, benzotriazole, Baylis Hillman acetates, N-substituted azole acrylates, ADDUCTS, FACILE, ACID, N-(2-AMINOBENZOYL)BENZOTRIAZOLE, ESTERIFICATION, BENZOTRIAZOLE, DERIVATIVES, IMIDAZOLES
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Anadolu Üniversitesi Adresli: Evet
Özet
N-Substituted methyl 2-((azolyl)methyl)-3-arylacrylates were synthesized stereo- and regioselectively with one-pot reaction between Baylis-Hillman acetates and a suitable acylazole in the presence of K2CO3 as a base catalyst. The targeted N-substituted azole acrylates were efficiently obtained in good yields (39%-89%).