Insecticidal activity of major lichen compounds, (-)- and (+)-usnic acid, against the larvae of house mosquito, Culex pipiens L.

ÇETİN H., TUFAN ÇETİN Ö., Turk A. O., Tay T., CANDAN M., Yanikoglu A., ...More

PARASITOLOGY RESEARCH, vol.102, no.6, pp.1277-1279, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 102 Issue: 6
  • Publication Date: 2008
  • Doi Number: 10.1007/s00436-008-0905-8
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1277-1279
  • Anadolu University Affiliated: Yes


In this research, (-)-usnic acid and (+)-usnic acid, commonly encountered lichen secondary metabolites, were evaluated for their insecticidal effects against the larvae of Culex pipiens L. (Diptera: Culicidae) under laboratory conditions. Both compounds showed strong larvicidal activity and caused 100% mortality on third-fourth larval stages of the species at 24 h at the doses of 5 and 10 ppm. Bioassays with (-)- and (+)-usnic acids against larvae of C. pipiens revealed that the LC50 values were 0.8 and 0.9 ppm, respectively. The results suggest that lichen compounds could be useful in the search of new insecticides.