Microwave assisted synthesis of ferrocene amides

EKTİ S. F., HÜR D.

INORGANIC CHEMISTRY COMMUNICATIONS, vol.11, no.9, pp.1027-1029, 2008 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 11 Issue: 9
  • Publication Date: 2008
  • Doi Number: 10.1016/j.inoche.2008.05.023
  • Journal Name: INORGANIC CHEMISTRY COMMUNICATIONS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
  • Page Numbers: pp.1027-1029
  • Keywords: ferrocene, ferrocene amide, benzotriazole, microwave, AMINO-ACIDS, DERIVATIVES
  • Anadolu University Affiliated: Yes

Abstract

A new microwave assisted synthesis methodology has been presented for the preparation of the ferrocene amides. Ferrocene carboxylic acid was derivatised using direct 1H-Benzotriazole/SOCl2 methodolgy to prepare N-ferrocenoyl benzotriazole as a new starting material for the functionalization of ferrocene ring. N-ferrocenoyl benzotriazole was reacted with mono- and di-amines under microwave irradiation to prepare ferrocene mono- and di-amides in high purity and in good yield. (C) 2008 Elsevier B.V. All rights reserved.