New Cyclohexylamine-dithiocarbamate Derivatives as Potential Anti-microbial Agents

YURTTAŞ L., KAYA ÇAVUŞOĞLU B., YILMAZ CANKILIÇ M., LEVENT S.

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.14, sa.11, ss.1308-1315, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 11
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1570180814666170412121402
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1308-1315
  • Anahtar Kelimeler: Dithiocarbamate, lipophilicity, antifungal activity, antibacterial activity, ADME, agents, ANTIBACTERIAL ACTIVITY, LIPOPHILICITY, DISCOVERY
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: In this study, 2-(substituted-sulfanyl)-N, N-dicyclohexylacetamide derivatives (2a-2g) and 2-(dicyclohexylamino)-2-oxoethyl-1-substituted carbodithioate derivatives (2h-2m) were synthesized and screened for their antimicrobial activity.