3-ACETYL-4-ARYL-5-OXO-2,7,7-TRIMETHYL-1,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES AND THEIR CALCIUM ANTAGONISTIC ACTIVITIES
ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, vol.45-2, no.11, pp.1154-1156, 1995 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 45-2 Issue: 11
- Publication Date: 1995
- Journal Name: ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
- Page Numbers: pp.1154-1156
- Keywords: 3-ACETYL-4-ARYL-5-OXO-2,7,7-TRIMETHYL-1,4,5,6,7,8-HEXAHYDROQUINOLINE DERIVATIVES, PHARMACOLOGY, SYNTHESIS, CALCIUM ANTAGONISTS, DIHYDROPYRIDINE, MODULATORS
- Anadolu University Affiliated: No
Abstract
Thirteen 3-acetyl-4-aryl-5-oxo-2,7,7-trimethyl-1,4,5,6,7,8-hexahydroquinoline derivatives (5a-m), one of which was synthesized before have been prepared. The structures of the products 5b-m were characterized by IR, H-1-NMR and elemental analyses The calcium antagonistic activity of these compounds was studied in rabbit taenia coli precontracted with I mmol/l Ca+2.