Chemical Composition and Antimicrobial Activity of the Essential Oils of Lavandula stoechas L. ssp stoechas Growing Wild in Turkey

KIRMIZIBEKMEZ H., Demirci B., YEŞİLADA E., BAŞER K. H. C., DEMİRCİ F.

NATURAL PRODUCT COMMUNICATIONS, cilt.4, sa.7, ss.1001-1006, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4 Sayı: 7
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1177/1934578x0900400727
  • Dergi Adı: NATURAL PRODUCT COMMUNICATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1001-1006
  • Anahtar Kelimeler: Lavandula stoechas ssp stoechas, Lamiaceae, essential oil, GC, GC-MS, alpha-fenchone, 1,8-cineole, camphor, antibacterial and anticandidal activity, ANTIFUNGAL ACTIVITY, ANTIBACTERIAL, ANGUSTIFOLIA, CONSTITUENTS, LAVENDER, OREGANO, PLANTS
  • Anadolu Üniversitesi Adresli: Evet

Özet

The chemical compositions of the essential oils obtained by hydrodistillation from file dried leaves and flowers of Lavandula stoechas L. ssp. stoechas were separately identified by GC-FID and GC-MS analyses. The main components were alpha-fenchone (41.9 +/- 1.2%), 1,8-cincole (15.6 +/- 0.8%), camphor (12.1 +/- 0.5%), and viridiflorol (4.1 +/- 0.4%) in the leaves; and alpha-fenchone (39.2 +/- 0.9%), myrtenyl acetate (9.5 +/- 0.4%), alpha-pinene (6.1 +/- 0.09%), camphor (5.9 +/- 0.05%) and 1,8-cincole (3.8 +/- 0.1%) in the flowers. Overall, 55 and 66 Constituents were identified in the leaf and flower essential oils representing more than 90% and 94% of the total, respectively. In addition, the essential oils were evaluated tor their antibacterial and anticandidal activities by broth rnicrodilution. The flower essential oil was found to be relatively more active than the leaf oil towards the tested pathogenic microorganisms. Methicillin-resistant Staphylococcus aureus was more susceptible to the flower oil (MIC= 31.2 mu g/mL). The oils, evaluated for their free radical Scavenging activity using a TLC-DPPH assay, were inactive at a concentration of 2 mg/mL.