Design of Lamivudine Loaded Nanoparticles for Oral Application by Nano Spray Drying Method: A New Approach to use an Antiretroviral Drug for Lung Cancer Treatment

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ÖZTÜRK A. A., Namli I., Gulec K., Gorgulu S.

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, vol.23, no.10, pp.1064-1079, 2020 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 23 Issue: 10
• Publication Date: 2020
• Doi Number: 10.2174/1386207323666200325155020
• Journal Name: COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
• Page Numbers: pp.1064-1079
• Keywords: Lamivudine, nanoparticle, nano spray dryer, anticancer, lung cancer, cytotoxicity, apoptosis, IN-VITRO CHARACTERIZATION, EUDRAGIT RS 100, ANNEXIN-V, CHITOSAN NANOPARTICLES, PLGA NANOPARTICLES, POLYMERIC NANOPARTICLES, TARGETED DELIVERY, VIVO EVALUATION, PARTICLE-SIZE, FORMULATION
• Anadolu University Affiliated: Yes

Abstract

Aims: To prepare lamivudine (LAM)-loaded-nanoparticles (NPs) that can be used in lung cancer treatment. To change the antiviral indication of LAM to anticancer.