Bioderived molecularly imprinted polymers in medical diagnostics platforms: Toward sustainable, point-of-care solutions
TrAC - Trends in Analytical Chemistry, vol.202, 2026 (SCI-Expanded, Scopus)
- Publication Type: Article / Review
- Volume: 202
- Publication Date: 2026
- Doi Number: 10.1016/j.trac.2026.118958
- Journal Name: TrAC - Trends in Analytical Chemistry
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, Chimica, Compendex, EMBASE, DIALNET, Academic Search Ultimate (EBSCO), Engineering Source (EBSCO)
- Keywords: Bioderived molecularly imprinted polymers, Biomedical sensing platforms, Eco-friendly biosensors, Green polymer sensors, Point-of-Care Testing (POCT), Sustainable diagnostics
- Anadolu University Affiliated: Yes
Abstract
The urgent global demand for rapid, accurate, and accessible medical diagnostics has driven the evolution of point-of-care testing (POCT) technologies. Among the emerging materials revolutionizing this field, bioderived molecularly imprinted polymers (MIPs) stand out as highly selective, robust, and environmentally friendly alternatives to traditional recognition elements. By combining the molecular recognition capabilities of synthetic polymers with renewable and biodegradable precursors, bioderived MIPs offer a transformative pathway toward sustainable, cost-effective, and portable diagnostic platforms. This review provides a comprehensive overview of the latest advancements in the design, fabrication, and integration of bioderived MIPs in POCT devices and their applications with a critical focus on the challenges and future directions in this rapidly evolving field. It highlights recent innovations in imprinting techniques using natural polymers, green solvents, and biodegradable matrices that meet both analytical performance and eco-compatibility. Furthermore, this review critically examines the environmental impact, regulatory considerations, and commercialization prospects of bioderived MIP-based diagnostics.