Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model

ARSLAN R., Bor Z., BEKTAŞ TÜRKMEN N., Mericli A. H., ÖZTÜRK Y.

THROMBOSIS RESEARCH, vol.127, no.3, pp.210-213, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 127 Issue: 3
  • Publication Date: 2011
  • Doi Number: 10.1016/j.thromres.2010.11.028
  • Journal Name: THROMBOSIS RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.210-213
  • Keywords: Crataegus orientalis, Carrageenan, Tail thrombosis model, Antithrombotic effect, ANTIOXIDANT ACTIVITIES, PLATELET-FUNCTION, IN-VITRO, FLAVONOIDS, RATS
  • Anadolu University Affiliated: Yes

Abstract

Introduction: Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular diseases. One of the main causes of multiple cardiovascular diseases is intravascular thrombosis and current agents, which are used for the treatment and prevention of thrombosis, have some side effects. Therefore, new antithrombotic and thrombolytic agents are still needed.