Synthesis and Evaluation of A New Series of Thiazole Derivatives as Potential Antitumor Agents and MMP Inhibitors

KAPLANCIKLI Z. A., ALTINTOP M. D., ATLI EKLİOĞLU Ö., SEVER B., BAYSAL M., TEMEL H. E., ...Daha Fazla

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.17, sa.5, ss.674-681, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1871520616666160802113620
  • Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.674-681
  • Anahtar Kelimeler: Thiazole, triazole, oxadiazole, anticancer activity, matrix metalloproteinase, MATRIX-METALLOPROTEINASE INHIBITORS, HUMAN BREAST-CANCER, OF-THE-LITERATURE, ANTICANCER AGENTS, IN-VITRO, PYRAZOLINE DERIVATIVES, HYDRAZONE DERIVATIVES, BIOLOGICAL EVALUATION, COLORECTAL-CANCER, CELL INVASION
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: In recent years, the relationship between overexpression of matrix metalloproteinases ( MMPs) and tumor invasion/metastasis has prompted researchers to develop MMP inhibitors as anticancer drugs.