Synthesis of Some New Thiazole Derivatives and Their Biological Activity Evaluation
JOURNAL OF CHEMISTRY, vol.2015, 2015 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 2015
- Publication Date: 2015
- Doi Number: 10.1155/2015/464379
- Journal Name: JOURNAL OF CHEMISTRY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Open Archive Collection: AVESIS Open Access Collection
- Anadolu University Affiliated: Yes
Abstract
New 2-(4-arylpiperazine-1-yl)-N-[4-(2-(4-substituted phenyl)thiazol-4-yl)phenyl]acetamide derivatives were synthesized and evaluated for their antimicrobial and anticholinesterase activities. Acetylcholinesterase inhibitory activities of the compounds were found weak contrary to expectations. It is unlikely that antifungal activity of the compounds was found significant, especially against Candida parapsilosis.