Inhibitory effects of carvacrol on DMBA induced pulmonary tumorigenesis in rats
Acta Pharmaceutica Turcica, cilt.40, sa.2, ss.93-98, 1998 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 40 Sayı: 2
- Basım Tarihi: 1998
- Dergi Adı: Acta Pharmaceutica Turcica
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.93-98
- Anahtar Kelimeler: Antitumor activity, Carvacrol
- Anadolu Üniversitesi Adresli: Evet
Özet
Essential oils of various plant species rich in carvacrol have several ethnomedical uses for various diseases in Turkey. Carvacrol, which was obtained by fractional distillation of Origanun onites L essential oil was tested for lung tumors induced by DMBA in rats in vivo and it was found to have strong antitumor activity at 0.1 mg·kg-1 i.p. Although the mechanism of action of antitumor activity of carvacrol was not investigated in this study, evidences for an inhibitory effect on angiogenesis were observed.