Synthesis of New Thiazolyl-pyrazoline Derivatives and Evaluation of Their Antimicrobial, Cytotoxic and Genotoxic Effects

SEVER B., ALTINTOP M. D., Gencer H., KAPKAÇ H. A., ATLI EKLİOĞLU Ö., BAYSAL M., ...Daha Fazla

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.15, sa.7, ss.744-756, 2018 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Sayı: 7
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1570180814666170925152902
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.744-756
  • Anahtar Kelimeler: Pyrazoline, thiazole, antimicrobial activity, cytotoxicity, genotoxicity, anticancer, THIOSEMICARBAZONE DERIVATIVES, BIOLOGICAL EVALUATION, ANTIFUNGAL ACTIVITY, POTENT ANTIFUNGAL, CANDIDA-ALBICANS, DRUG DISCOVERY, CANCER, RESISTANCE, INHIBITORS, MECHANISMS
  • Anadolu Üniversitesi Adresli: Evet

Özet

Background: Pyrazolines have played a pivotal role in antimicrobial and anticancer drug discovery. Moreover, thiazoles have attracted a great deal of interest due to their crucial roles in the lead identification and optimization.