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Turan-Zitouni G., Demirayak E., ÖZDEMİR A., KAPLANCIKLI Z. A., Yildiz M.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol.39, no.3, pp.267-272, 2004 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
39
Issue:
3
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Publication Date:
2004
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Doi Number:
10.1016/j.ejmech.2003.11.001
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Journal Name:
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Index Chemicus (IC)
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Page Numbers:
pp.267-272
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Keywords:
thiazole, benzothiazole, benzimidazole, benzoxazole, antimicrobial activity, WATER MARINE SPONGES, BENZIMIDAZOLE DERIVATIVES, MICROBIOLOGICAL ACTIVITY, FAMILY PACHASTRELLIDAE, REVERSE-TRANSCRIPTASE, BENZOXAZOLES, ALKALOIDS, OXAZOLO(4,5-B)PYRIDINES, ZIDOVUDINE, L-697,661
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Anadolu University Affiliated:
Yes
Abstract
Some 2-[(benzazole-2-yl)thioacetylamino]thiazole derivatives (III) were synthesized by reacting 4-methyl-2-(chloroacetylamino)thiazole derivatives (I) with benzazol-2-thiole (II) in acetone in the presence of K2CO3. The chemical structures of the compounds were elucidated by H-1 NMR and FAB(+)-MS spectral data. The prepared compounds were tested for antimicrobial activity and toxicity. (C) 2003 Elsevier SAS. All rights reserved.