Ferulagone: A new monoterpene ester from Ferulago thirkeana essential oil

Baser K., Demirci B., DEMİRCİ F., Hashimoto T., Asakawa Y., Noma Y.

PLANTA MEDICA, cilt.68, sa.6, ss.564-567, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Sayı: 6
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1055/s-2002-32557
  • Dergi Adı: PLANTA MEDICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.564-567
  • Anadolu Üniversitesi Adresli: Evet

Özet

Essential oil obtained by micro-distillation and hydrodistillation of the endemic Ferulago thirkeana (Boiss.) Boiss. (Apiaceae) was analysed by GC/MS. An unknown component isolated from the essential oil was characterized by chromato-spectral techniques (1D-, 2D-NMR, HRMS, IR and UV) as (1S)-2,6,6-trimethyl-4-oxobicyclo[3.1.1]hept-2-enyl(2E)-2-methylbut-2-enoate (= ferulagone or 1-angeloyloxyverbenone) (1). Biological activities of the essential oil and the purified major component (1) were tested against various human pathogenic microorganisms resulting in moderate inhibition (62.5-125 mug/ml).