A Series of Furan-based Hydrazones: Design, Synthesis, and Evaluation of Antimicrobial Activity, Cytotoxicity and Genotoxicity

ALTINTOP, MEHLİKA; SEVER, BELGİN; ATLI EKLİOĞLU, ÖZLEM; BAYSAL, MERVE; Demirel, Rasime; ÖZDEMİR, AHMET

doi:10.2174/1570180816666190325163948

A Series of Furan-based Hydrazones: Design, Synthesis, and Evaluation of Antimicrobial Activity, Cytotoxicity and Genotoxicity

ALTINTOP M. D., SEVER B., ATLI EKLİOĞLU Ö., BAYSAL M., Demirel R., ÖZDEMİR A.

LETTERS IN DRUG DESIGN & DISCOVERY, vol.17, no.3, pp.312-322, 2020 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 17 Issue: 3
Publication Date: 2020
Doi Number: 10.2174/1570180816666190325163948
Journal Name: LETTERS IN DRUG DESIGN & DISCOVERY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Agricultural & Environmental Science Database, Biotechnology Research Abstracts, EMBASE
Page Numbers: pp.312-322
Keywords: Antimicrobial activity, cytotoxicity, furan, genotoxicity, hydrazone, molecular docking, IN-VITRO EVALUATION, BIOLOGICAL EVALUATION, DERIVATIVES, AGENTS, ANTIFUNGAL
Anadolu University Affiliated: Yes

Abstract

Background: Hydrazones, frequently occurring motifs in many bioactive molecules, have attracted a great deal of interest as potent antimicrobial agents.