Oxidative stress and mRNA expression of acetylcholinesterase in the leukocytes of ischemic patients

IŞIK M., BEYDEMİR Ş., Yilmaz A., Naldan M. E., Aslan H. E., GÜLÇİN İ.

BIOMEDICINE & PHARMACOTHERAPY, vol.87, pp.561-567, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 87
  • Publication Date: 2017
  • Doi Number: 10.1016/j.biopha.2017.01.003
  • Journal Name: BIOMEDICINE & PHARMACOTHERAPY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.561-567
  • Keywords: Gene expression, Ischemic stroke, Oxidative stress, Free radical, Acetylcholinesterase, GLUTATHIONE-S-TRANSFERASE, ALZHEIMERS-DISEASE, PROTEIN OXIDATION, STROKE, THERAPY, BRAIN, DIFFERENTIATION, REPERFUSION, BIOMARKERS, SYSTEM
  • Anadolu University Affiliated: Yes

Abstract

Background: Pathogenesis of ischemic brain injury is occurred by crucial metabolic reasons. For instance, oxidative stress from free radical generation is causing to the thrombotic cerebrovascular stroke. In this case, the measurement of the oxidative stress is very important for a better understanding of the stroke pathophysiology. Because, the oxidative stress in stroke is generally assumed as one of the mechanisms taking part in neuronal damage. Thus, oxidative stress has a vital role in the cholinergic system.