Analysis of anticancer drugs using thin layer chromatography- A review

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YENİCELİ UĞUR D., Ugur A.

JOURNAL OF RESEARCH IN PHARMACY, vol.22, no.3, pp.334-346, 2018 (ESCI) identifier identifier

  • Publication Type: Article / Review
  • Volume: 22 Issue: 3
  • Publication Date: 2018
  • Doi Number: 10.12991/jrp.2018.72
  • Journal Name: JOURNAL OF RESEARCH IN PHARMACY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.334-346
  • Keywords: Thin layer chromatography, anticancer drugs, biological fluids, pharmaceuticals, plants, STABILITY-INDICATING HPTLC, HIGH-PERFORMANCE, ENDOPHYTIC FUNGUS, PLANAR CHROMATOGRAPHY, QUALITY-CONTROL, BULK DRUG, QUANTITATIVE-ANALYSIS, SEPARATION METHODS, TLC, TAXOL
  • Anadolu University Affiliated: Yes

Abstract

Cancer is a fatal disease and cancer incidence is increasing from day to day. Thus, anticancer drugs are widely used and their analysis requires simple and effective analytical procedures. Thin layer chromatography (TLC) is a promising technique for drug analysis as a simple and versatile technique with low cost of analysis, minimal sample clean-up and high sample loading capacity. An extensive literature survey has been done and TLC techniques used for the analysis of anticancer agents in different matrices have been presented.